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Asiatic Acid & Madecassic Acid (Centella triterpene acids)

Asiatic Acid · Madecassic AcidSoothing

The free triterpene acids from centella (cica). In lab studies they raised collagen-I output by skin cells — a mechanism, not a proven visible result.

What it does

Asiatic acid and madecassic acid are two of the active triterpene compounds in Centella asiatica (cica). In cell-culture studies they stimulated type-I collagen production by skin fibroblasts, and the effect was greater when vitamin C was present (vitamin C is a cofactor for collagen formation). That makes pairing them with vitamin C mechanistically reasonable. The important caveat: this is in-vitro evidence — a plausible mechanism, not proof of a visible result on real skin, which would need clinical trials. Centella as a whole is better known for its soothing, barrier-supporting profile.

The evidence, graded

emergingIn lab studies, asiatic acid and madecassic acid (the triterpene acids from centella) raised type-I collagen output by skin fibroblasts, and the effect was greater when vitamin C was also present. This is in-vitro evidence — a plausible reason to pair them, not a proven visible result on real skin.Bonté 1994 · Planta Medica ↗

Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.

Also known as

centella acids, triterpene acids

Pairs worth knowing

L-Ascorbic Acid (Vitamin C) · works together ↗Centella Asiatica (Cica) · works together ↗

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