Copper Tripeptide-1 (GHK-Cu)
A copper-bound peptide popular in serums marketed for aging skin — but the best controlled study found no objective improvement, only higher user satisfaction.
What it does
Copper tripeptide-1 (GHK-Cu) is a small peptide complexed with copper, widely marketed as a repair and rejuvenation ingredient. The honest evidence picture is weaker than the marketing: in a controlled post-laser trial, a GHK-Cu regimen showed no statistically significant objective improvement in wrinkles, redness, or overall skin quality versus control — the only thing that improved was how satisfied users said they were. It is well tolerated, so there is little downside to using it, but you shouldn't expect a visible change on the strength of the current evidence. Spend your effort and budget on actives with stronger backing: retinoids, vitamin C, and daily sunscreen.
The evidence, graded
Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.
Also known as
ghk-cu, copper peptide, tripeptide-1