Cited skincare — peer-reviewed evidence, no upsell.
He

Hexapeptide-11

Hexapeptide-11Active

A yeast-derived peptide with an interesting lab story (cellular-senescence markers) but no clinical proof of a visible effect — promising-but-unproven.

What it does

Hexapeptide-11 is a small peptide derived from yeast. In cell-culture studies it lowered markers of cellular senescence in aged skin cells, which is a plausible cellular mechanism relevant to skin aging. But that evidence is entirely in-vitro: no clinical trial has shown that it produces a visible change on real skin. The honest framing is promising-but-unproven — a gentle, well-tolerated supporting ingredient rather than something to expect results from on its own.

The evidence, graded

emergingHexapeptide-11 lowered markers of cellular senescence in cultured skin cells. This is lab (in-vitro) evidence only — no clinical trial has shown a visible effect on real skin, so treat it as promising-but-unproven.Gruber 2013 · Journal of Cosmetic Science ↗

Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.

This page is public and indexed on purpose (unlike profiles and drops, which are unlisted) — it’s the citation behind shared ingredient cards, and it should be findable.
Want more like this?
Get Drop, free. Every flag cites its source, the app tells you when your routine is complete, and it helps you simplify — instead of selling you more products.
Get the free appHow Drop works