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Hexapeptide-11
Hexapeptide-11Active
A short protein piece first found in yeast. It’s only been tested on cells in a dish, not on skin.
What it does
It’s a short protein piece first found in yeast. In one lab study it changed when aging skin and hair-follicle cells stopped dividing, but that was cells in a dish. It hasn’t been tested on skin, so there’s no visible result to expect and no data on how skin tolerates it.
The evidence, graded
emergingIn one lab study, hexapeptide-11 changed when aged skin cells and hair-follicle cells entered senescence, the state in which aging cells stop dividing, at strengths of 0.1% to 1.0%. The authors believe it works by lowering two proteins, ATM and p53. The study tested no skin and no people, so it shows nothing about a visible result or how skin tolerates it.Gruber 2013 · Journal of Cosmetic Science ↗
Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.
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