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Hexapeptide-11

Hexapeptide-11Active

A yeast-derived peptide with an interesting lab story (cellular-senescence markers) but no clinical proof of a visible effect — promising-but-unproven.

What it does

Hexapeptide-11 is a small peptide derived from yeast. In cell-culture studies it lowered markers of cellular senescence in aged skin cells, which is a plausible cellular mechanism relevant to skin aging. But that evidence is entirely in-vitro: no clinical trial has shown that it produces a visible change on real skin. The honest framing is promising-but-unproven — a gentle, well-tolerated supporting ingredient rather than something to expect results from on its own.

The evidence, graded

emergingHexapeptide-11 lowered markers of cellular senescence in cultured skin cells. This is lab (in-vitro) evidence only — no clinical trial has shown a visible effect on real skin, so treat it as promising-but-unproven.Gruber 2013 · Journal of Cosmetic Science ↗

Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.

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