Cited skincare — every flag names its source, no upsell.Sy
Syn-Ake
Dipeptide Diaminobutyroyl Benzylamide DiacetateActive
A peptide sold as a needle-free wrinkle relaxer — evidence is weak; expect mild surface smoothing, not injection-like results.
What it does
It’s a lab-made peptide sold as a cream alternative to wrinkle-relaxing injections. In theory it blocks the nerve signal that tightens muscles, but it’s too big to reach the muscle, so evidence it works on skin is weak. Expect mild surface smoothing like other peptides, not injection-like results.
The EU’s ingredient database lists it as a skin conditioner, its general term for an ingredient that keeps skin in good condition.European Commission, CosIng (© European Union, CC BY 4.0) · uses put in plain words by Drop ↗
The evidence, graded
strongPal-KTTKS (Matrixyl) has the most trials. A placebo-controlled study applied 0.005% around one eye twice daily for 28 days: fold depth down 18%, fold thickness down 37%, by profilometry. A 12-week split-face trial of 3 ppm reduced wrinkles and fine lines, and a four-month study improved roughness and wrinkle depth. Copper peptide (GHK-Cu) reaches Drop through a review; its placebo-controlled studies all ran 12 weeks, and its one earlier measurement is collagen in thigh biopsies at a month.Robinson 2005 · International Journal of Cosmetic Science ↗ Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.
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