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Cy

Cyanocobalamin (Vitamin B12)

Cyanocobalamin

Vitamin B12. A B12 cream helped eczema in one small study; B12 pills and shots are linked to acne flares.

What it does

Cyanocobalamin is a stable form of vitamin B12. One reported study found a 0.07% B12 cream, used for 8 weeks, improved atopic dermatitis. B12 supplements have been linked with worsening existing acne. B12 injections have caused breakouts and allergic reactions, including in people allergic to cobalt. Whether B12 in a skincare product can do this has not been studied in anything Drop has read.

The evidence, graded

expert consensusA review of B vitamins in dermatology reports that a 0.07% B12 (cyanocobalamin) cream, used for 8 weeks on one side of the body, significantly improved atopic dermatitis. It also reports that B12 supplements were linked with worsening existing acne. B12 injections have caused breakouts and allergic reactions, including in people allergic to cobalt. It does not say whether B12 in a cosmetic can do this.Elgharably 2023 · Dermatology Reports ↗

Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.

Also known as

vitamin b12, cobalamin, cyanocobalamin

Pairs worth knowing

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