Gr
Grape Leaf Extract
Vitis Vinifera (Grape) Leaf Extract · Vitis Vinifera Leaf Extract
An extract from the wine grape, Vitis vinifera. Little research tests what it does on skin.
What it does
It’s an extract of the leaves of the wine grape vine. The EU lists it as a skin conditioner.
The EU’s ingredient database lists it as a skin conditioner, its general term for an ingredient that keeps skin in good condition.European Commission, CosIng (© European Union, CC BY 4.0) · uses put in plain words by Drop ↗
The evidence, graded
expert consensusUS safety reviewers (2014) judged 24 grape-derived ingredients safe as used, grape seed, leaf and juice extract among them. In tests on people, products with 0.5% juice extract, and seed extract at up to 1% of a raw material, didn’t irritate or cause allergy. They treated one rabbit test of undiluted seed extract, which found moderate irritation, as an outlier. Grape ingredients don’t appear to irritate or cause allergy, they said, and makers should limit pesticides and heavy metals.Fiume 2014 · International Journal of Toxicology ↗
Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.
Browse all 1238 ingredients — grouped by what they do, each with whatever evidence we can cite.
This page is public so a shared ingredient card always has its sources behind it — and so you can check them without an account.
Want more like this?
Every evidence-based flag cites its source, Drop tells you when your routine is complete, and it helps you simplify — instead of selling you more. The app launches on iOS and Android in October 2026. Rate my routine works today at /rate — no sign-in.