Is
Isotretinoin
IsotretinoinActive
Oral retinoid prescribed for severe acne. Drop tracks the topical entry; oral use is strictly a derm conversation.
What it does
Isotretinoin is taken orally (most often as a 4-6 month course) for severe nodulocystic acne. Side effects can be significant and require medical monitoring. We surface the contraindication in case it appears in a user's product list, but this is not a routine ingredient — it's a derm-supervised treatment.
The evidence, graded
strongAll topical retinoids — tretinoin, adapalene, retinol, retinaldehyde, retinyl palmitate, and hydroxypinacolone retinoate — are not recommended during pregnancy. Direct human data exist mainly for the prescription retinoids (tretinoin, adapalene); the caution extends to the others as a precautionary class-effect. Data on inadvertent exposure reassure but aren't strong enough to recommend any retinoid in pregnancy.Kaplan 2015 · British Journal of Dermatology ↗
Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.
Also known as
accutane, 13-cis retinoic acid
This page is public and indexed on purpose (unlike profiles and drops, which are unlisted) — it’s the citation behind shared ingredient cards, and it should be findable.
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