Ne
Neopentyl Glycol Diethylhexanoate
Neopentyl Glycol DiethylhexanoateBarrier
An oil-like ingredient made from neopentyl glycol, used to soften skin.
What it does
It’s made by joining neopentyl glycol to two molecules of 2-ethylhexanoic acid. It works like an oil, softening skin.
The evidence, graded
expert consensusUS safety reviewers (2017) judged a group of related esters safe as used, propanediol dicaprylate/caprate and neopentyl glycol diethylhexanoate among them; both soften skin. At up to full strength, neither caused allergy in repeat patch tests on people. Absorbed and broken down, neopentyl glycol diethylhexanoate gives 2-ethylhexanoic acid, which can harm the liver and reproduction. It’s used at up to 57%, but the reviewers judged the acid is cleared too fast to reach harmful levels.Becker 2017 · Cosmetic Ingredient Review ↗
Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.
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