Cited skincare — every flag names its source, no upsell.
Pa

Palmitoyl Tripeptide-5

Palmitoyl Tripeptide-5Active

A lab-made peptide sold as a signal to make collagen. Independent tests of it on its own are few.

What it does

It’s sold as a signal that tells skin cells to make more collagen, by mimicking part of a natural signaling protein. Most studies on it are supplier-funded or test creams with many ingredients; independent trials of it alone are few.

The EU’s ingredient database lists it as a skin conditioner, its general term for an ingredient that keeps skin in good condition.European Commission, CosIng (© European Union, CC BY 4.0) · uses put in plain words by Drop ↗

The evidence, graded

moderateA 2021 review of 88 face products for sensitive skin found peptides in 17% of them, palmitoyl tripeptide-5 among the seven named. The authors say the data for these peptides are mostly found in patents and supplier brochures, not in randomized placebo-controlled studies.Resende 2021 · Pharmaceuticals (Basel) ↗

Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.

Also known as

syn-coll, palmitoyl kvk

Browse all 1238 ingredients — grouped by what they do, each with whatever evidence we can cite.

This page is public so a shared ingredient card always has its sources behind it — and so you can check them without an account.
Want more like this?
Every evidence-based flag cites its source, Drop tells you when your routine is complete, and it helps you simplify — instead of selling you more. The app launches on iOS and Android in October 2026. Rate my routine works today at /rate — no sign-in.
See what Drop doesHow Drop works