Ce
Ceramides
Ceramide NP · Ceramide AP · Ceramide EOPBarrier
Lipid molecules that fill the spaces between skin cells. Replenishing them supports a damaged or aging barrier.
What it does
Ceramides make up about half of the skin's intercellular lipids; they decline with age and are stripped by harsh cleansing or active ingredients. Topical ceramides — especially in a 3:1:1 ratio with cholesterol and fatty acids — replenish the barrier.
The evidence, graded
strongThe skin's barrier is built from ceramides, cholesterol, and free fatty acids in a roughly 1:1:1 to 3:1:1 ratio. Moisturizers formulated to mimic that ratio support barrier repair more than any one lipid alone.Man 1996 · Journal of Investigative Dermatology ↗
expert consensusCeramide products are barrier-supportive and pair safely with all actives. Layering ceramides after an irritating active is a common tolerance strategy.Draelos 2018 · Journal of Cosmetic Dermatology ↗
Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.
Also known as
ceramides, ceramide np
Pairs worth knowing
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