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Panthenol (Pro-vitamin B5)

Panthenol · Dexpanthenol · Pantothenic Acid · Calcium PantothenateSoothing

Provitamin B5. Humectant + soothing + supports barrier recovery.

What it does

Panthenol is converted to pantothenic acid (B5) in the skin. Improves hydration, soothes irritation, and supports recovery after barrier-disrupting treatments (acids, retinoids, sun).

The evidence, graded

expert consensusPanthenol is barrier-supportive and pairs safely with all actives. It's commonly used to reduce retinoid and AHA irritation as part of 'sandwich' tolerance strategies.Proksch 2002 · Journal of Dermatological Treatment ↗

Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.

Also known as

pro-vitamin b5, dexpanthenol, vitamin b5, pantothenic acid

Pairs worth knowing

Retinol · works together ↗Niacinamide (Vitamin B3) · works together ↗Ceramides · works together ↗Hyaluronic Acid · works together ↗

Read more

Routines · 5 minSkincare for the Gym: Before, During, and After SweatSweat plus sunscreen plus friction is a recipe for breakouts and irritation. Here is what to do before a workout, during, and after to keep skin clear.

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