Cited skincare — every flag names its source, no upsell.Sh
sh-Oligopeptide-1 (EGF)
sh-Oligopeptide-1Active
A lab-made growth factor tied to skin repair and renewal. It’s a big molecule, so most of it likely stays on the surface.
What it does
It’s a lab-made version of epidermal growth factor, a signaling protein involved in healing and skin renewal. It’s a large protein, and most studies suggest it stays mostly on the surface unless the product helps it get in. It’s common in Korean and high-end serums.
The EU’s ingredient database lists it as a skin conditioner, its general term for an ingredient that keeps skin in good condition.European Commission, CosIng (© European Union, CC BY 4.0) · uses put in plain words by Drop ↗
The evidence, graded
strongPal-KTTKS (Matrixyl) has the most trials. A placebo-controlled study applied 0.005% around one eye twice daily for 28 days: fold depth down 18%, fold thickness down 37%, by profilometry. A 12-week split-face trial of 3 ppm reduced wrinkles and fine lines, and a four-month study improved roughness and wrinkle depth. Copper peptide (GHK-Cu) reaches Drop through a review; its placebo-controlled studies all ran 12 weeks, and its one earlier measurement is collagen in thigh biopsies at a month.Robinson 2005 · International Journal of Cosmetic Science ↗ Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.
Also known as
epidermal growth factor, oligopeptide-1
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