Cited skincare — every flag names its source, no upsell.
Sh

sh-Oligopeptide-1 (EGF)

sh-Oligopeptide-1Active

Recombinant epidermal growth factor. Promoted for cellular renewal; potency vs marketing claim is debated.

What it does

sh-Oligopeptide-1 is a recombinant version of epidermal growth factor (EGF), a signaling protein involved in skin healing and cellular turnover. Topical penetration of a 6.2 kDa protein is challenging — most studies suggest the active form mostly stays at the surface unless the formulation includes a delivery vehicle. Common in K-beauty and high-end Western 'rejuvenation' serums. The benefits-vs-cost tradeoff is best evaluated against the rest of the routine.

The evidence, graded

strongMost cosmetic peptides (Matrixyl, copper peptides, palmitoyl tripeptide-1) show measurable firmness or elasticity changes in 8–12 weeks of consistent twice-daily use. Visible benefits are typically subtle compared to retinoids.Robinson 2005 · International Journal of Cosmetic Science ↗

Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.

Also known as

egf, epidermal growth factor, oligopeptide-1

Pairs worth knowing

Niacinamide (Vitamin B3) · works together ↗Hyaluronic Acid · works together ↗Ceramides · works together ↗Centella Asiatica (Cica) · works together ↗

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