Cited skincare — every flag names its source, no upsell.
Gl

Gluconolactone

GluconolactoneExfoliant

Polyhydroxy acid (PHA). Same chemical-exfoliation principle as AHAs, with a much gentler skin-tolerance profile.

What it does

Gluconolactone is a larger molecule than glycolic or lactic acid, so it penetrates the skin more slowly. The result is similar surface-level exfoliation with markedly less stinging, redness, or photosensitivity. Often the first acid recommended for sensitive skin, rosacea-prone skin, or compromised-barrier states. Pairs without compounding irritation alongside niacinamide, peptides, and (for tolerated users) a low-percent retinoid.

The evidence, graded

emergingAHAs (glycolic, lactic, mandelic) need an acidic pH (typically 3.5–4) to deliver advertised exfoliation. Products with neutral or partially neutralized pH still hydrate but won't drive meaningful keratolysis.Smith 1996 · Journal of the American Academy of Dermatology ↗

Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.

Also known as

pha, polyhydroxy acid

Pairs worth knowing

Niacinamide (Vitamin B3) · works together ↗Hyaluronic Acid · works together ↗Ceramides · works together ↗Panthenol (Pro-vitamin B5) · works together ↗

Browse all 668 ingredients — grouped by what they do, each with whatever evidence we can cite.

This page is public so a shared ingredient card always has its sources behind it — and so you can check them without an account.
Want more like this?
Every evidence-based flag cites its source, Drop tells you when your routine is complete, and it helps you simplify — instead of selling you more. The app launches on iOS and Android in October 2026. Rate my routine works today at /rate — no sign-in.
See what Drop doesHow Drop works