Cited skincare — peer-reviewed evidence, no upsell.
Pe

Pentaerythrityl Tetraisostearate

Pentaerythrityl TetraisostearateBarrier

Synthetic ester emollient. Cushioning skin feel; common in 'silicone-free' moisturizers as a silicone alternative.

What it does

Pentaerythrityl tetraisostearate is a heavier ester emollient that gives formulations a silicone-like cushioning feel without using silicones. Common in moisturizers and lipsticks marketed as silicone-free. Higher comedogenic potential than caprylic/capric triglyceride, so worth flagging on acne-prone skin if it's high on the INCI.

The evidence, graded

moderateSome occlusives (cocoa butter, coconut oil, isopropyl myristate, certain plant butters) can be comedogenic on acne-prone skin. Lighter occlusives (squalane, mineral oil, hyaluronic acid, glycerin) are generally non-comedogenic in published data.Kligman 1972 · Archives of Dermatology

Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.

Also known as

pti

Pairs worth knowing

This page is public and indexed on purpose (unlike profiles and drops, which are unlisted) — it’s the citation behind shared ingredient cards, and it should be findable.
Want more like this?
Get Drop, free. Every flag cites its source, the app tells you when your routine is complete, and it helps you simplify — instead of selling you more products.