As
Asiaticoside
AsiaticosideSoothing
One of the main compounds in centella. Small studies found fewer lip lines and thinner facial scars.
What it does
It’s one of four main compounds in centella. Most of its wound-repair research is in lab and animal studies. In people, a lipstick with asiaticoside reduced lip wrinkles over 8 weeks, and in an observational study of stitched facial cuts, asiaticoside users had the thinnest scars.
The evidence, graded
strongKongkaew et al. (2020) reviewed five double-blinded randomized trials of Centella asiatica on wrinkles in 172 Asian women. In one, asiaticoside applied as a lipstick for 8 weeks reduced lip wrinkling. The authors add that lack of C. asiatica standardization prevents general application.Kongkaew 2020 · Journal of Cosmetic Science ↗
moderateHu et al. (2023), an observational study of 127 patients with post-suturing facial scars, compared silicone, onion extract, asiaticoside and no treatment. The silicone, onion extract and asiaticoside groups had narrower scars and lower scar scale scores, and the asiaticoside group had the thinnest scar.Hu 2023 · American Journal of Translational Research ↗
Graded per the methodology: strong · moderate · emerging · expert consensus. A weak source on a strong claim gets the weaker label.
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