Skincare without the upsell.
Sh

sh-Oligopeptide-3 (IGF-1)

sh-Oligopeptide-3 · SH-Oligopeptide-3 · Oligopeptide-3Active

Recombinant IGF-1 peptide. Found in growth-factor serums alongside EGF; skin penetration of large peptides is debated.

What it does

sh-Oligopeptide-3 is a synthetic peptide modeled on IGF-1, a protein that signals skin cell growth. It appears in premium growth-factor serums, usually alongside EGF. Large peptide molecules have trouble crossing the outer skin layer. Most evidence comes from small or supplier-funded studies. Generally well-tolerated.

Also known as

oligopeptide-3, sh-igf-1 peptide

Pairs worth knowing

Browse all 656 ingredients — grouped by what they do, each with whatever evidence we can cite.

This page is public and indexed on purpose (unlike profiles and drops, which are unlisted) — it’s the citation behind shared ingredient cards, and it should be findable.
Want more like this?
Every evidence-based flag cites its source, Drop tells you when your routine is complete, and it helps you simplify — instead of selling you more. The app lands on iOS and Android soon; the cited read at /rate works today, no sign-in.